Phospho-yap ser127
WebPhospho-YAP1 (Ser127) Antibody (PA5-121279) in ICC/IF Immunocytochemical analysis of Phospho-YAP1 (Ser127) in HeLa cells using a Phospho-YAP1 (Ser127) Polyclonal … WebYAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. YAP can act both as a coactivator and corepressor and is the critical downstream regulatory target in the Hippo signaling pathway.
Phospho-yap ser127
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WebWestern blot analysis of extracts from HeLa cells (lane 1) or YAP knock-out cells (lane 2) using Phospho-YAP (Ser127) (D9W2I) Rabbit mAb #13008 (upper), and GAPDH (D6H11) … WebJan 28, 2013 · The core Hippo pathway kinase Lats phosphorylates YAP directly at Ser127, which causes YAP cytoplasmic retention . EGF treatment reduced overall YAP phosphorylation and YAP phosphorylation at Ser127 in a time-dependent manner in confluent serum-starved MCF-10A cells ( Fig. 1 E and F and Fig. S2 B ), suggesting that …
WebPhospho-YAP (Ser127) (D9W2I) Rabbit mAb recognizes endogenous levels of YAP protein only when phosphorylated at Ser127. This antibody may cross-react with phospho-TAZ (Ser89). Species Reactivity: Human, Mouse, Rat Source / Purification WebJul 30, 2024 · Western blot showed increased expression of LATS1, YAP, and TEAD, but decreased phosphorylation of YAP on the site of ser127 in 14 or 28 days post-IRI kidneys, compared with the sham mice ...
WebApr 11, 2024 · The heightened phospho-YAP levels at Ser127 in protein samples were procured three- and six days post-infection (dpi), indicating the stimulation of the Hippo signaling pathway in COVID-19. The... WebInvitrogen Anti-Phospho-YAP1 (Ser127) Polyclonal, Catalog # PA5-117322. Tested in Western Blot (WB) applications. This antibody reacts with Human samples. Supplied as 100 µL purified antibody (0.18 mg/mL). ... YAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its ...
WebDec 15, 2016 · YAP(S128D), carrying a permanent phospho-mimetic substitution at Ser128, showed constitutive nuclear localisation even upon increased Ser127 phosphorylation. This indicates that Ser128 phosphorylation (as mimicked by S128D) can override YAP regulation through Ser127 phosphorylation.
WebOct 6, 2024 · The Phospho-YAP (Ser127) (D9W2I) Rabbit mAb Antibody from Cell Signaling Technology is a Rabbit Monoclonal antibody to YAP1, and Yes1 associated transcriptional regulator. This antibody recognizes Human, Mouse, and Rat antigen. The Phospho-YAP (Ser127) (D9W2I) Rabbit mAb Antibody has been validated for the following applications: … popular things in south americaWebPolyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser127 of human YAP. Antibodies are purified by protein A and peptide affinity chromatography. Validations. None provided. Applications. Western Blotting (WB) Reactivity. Homo sapiens (Human) Mus musculus (House mouse) sharks found in hawaiiWebApr 19, 2024 · The following antibodies were used: anti-YAP (Cell Signaling Technology, 4912 s), phospho-YAP (Ser127) (Cell Signaling Technology, #4911), β-actin (Santa Cruz, sc-1615), cleaved-PARP (Santa Cruz, sc-7150). ... sorafenib and CT-707 response in hypoxia. On the left, hypoxia caused decreased levels of p-YAP (Ser127), denoting the nuclear ... sharks freeze to death newsWebApr 11, 2024 · Our results showed that the phosphorylation levels of YAP at Ser127 were significantly lower in S1PR2-overexpressing HLSECs (Figure 6B), while higher in S1PR2-silencing HLSECs, suggesting that S1PR2 signaling inhibits phosphorylation of YAP at Ser127 and thus shifts its nuclear localization in HLSECs (Figure 6A,B). sharks friendshipWebMonoclonal Antibody for studying YAP (Ser127) non-phosphate. Cited in 3 publications. Validated for Western Blotting. Highly specific and rigorously validated in-house, Non … popular things in greeceWebPhospho-YAP1 (Ser127) Recombinant Rabbit Monoclonal Antibody (3F3) Advanced Verification This Antibody was verified by Cell treatment to ensure that the antibody binds … sharks found living in underwater volcanohttp://asbio.com.cn/shop/category/1-383/page/10 popular things in the 1970s