List of platinum based chemotherapy agents

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August undefined, 2024

Web28 mrt. 2024 · Zejula is indicated: • as monotherapy for the maintenance treatment of adult patients with advanced epithelial (FIGO Stages III and IV) high-grade ovarian, fallopian tube or primary peritoneal cancer who are in response (complete or partial) following completion of first-line platinum-based chemotherapy. Web17 jul. 2012 · Platinum-based chemotherapy drugs are among the most powerful and widely used against cancer. However, they have toxic side effects, and tumors can become resistant to them.

Survival benefit of platinum-based regimen in early stage triple ...

Web3 mrt. 2008 · Unfortunately, resistance has limited the efficacy of these agents in most diseases. Resistance to platinum-based chemotherapy can be intrinsic or acquired and may be mediated by factors outside or within the cancer cell or at its cell membrane. Resistance to platinum chemotherapy is multifactorial (2–6). WebComparison of single agent versus combined chemotherapy in previously treated patients with advanced urothelial carcinoma: a meta-analysis Xiao-Jun Wu, Yi Zhi, Peng He, Xiao-Zhou Zhou, Ji Zheng, Zhi-Wen Chen, Zhan-Song Zhou Institute of Urinary Surgery, Southwest Hospital, Third Military Medical University, Chongqing, People’s Republic of … smart home oplossingen

Inclusion of Platinum Agents in Neoadjuvant Chemotherapy …

Web20 jul. 2024 · Platinum-based chemotherapy with cisplatin (the prototype of platinum agents) and its derivatives, carboplatin and oxaliplatin, is traditionally the first-line cytotoxic treatment of lung, colorectal, ovarian, breast, head/neck, bladder and testicular cancers [].An expected side effect of these widely administered platinum-containing regimens is … This is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer. This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision. Each drug is listed once (at present), … Meer weergeven • Altretamine • Bendamustine • Busulfan • Carboquone • Carmustine Meer weergeven • Ixabepilone Meer weergeven • Vorinostat • Romidepsin Meer weergeven • Etoposide • Teniposide • Tafluposide Meer weergeven Aclarubicin • Daunorubicin • Doxorubicin • Epirubicin Meer weergeven • Abraxane • Cabazitaxel • Docetaxel • Larotaxel Meer weergeven • Belotecan • Camptothecin • Exatecan • Gimatecan • Irinotecan • Topotecan Meer weergeven WebComparison of single agent versus combined chemotherapy in previously treated patients with advanced urothelial carcinoma: a meta-analysis Xiao-Jun Wu, Yi Zhi, Peng He, Xiao … smart home optimum axa

Comparison of single agent versus combined chemotherapy in …

Chemotherapy: Pt anticancer agents - Chemistry LibreTexts

WebThe trial demonstrated statistically significant improvements in OS and PFS for patients receiving cemiplimab-rwlc compared to those treated with platinum-based chemotherapy. Web13 apr. 2024 · Eighty-nine percent of patients previously received androgen-signaling inhibitor(s), 68% had platinum-based chemotherapy, and 50% had prior taxane chemotherapy. The median duration of follow-up was 30.8 weeks (range, 1.9-86.9), and the median duration of treatment was 9 weeks (range, 0.7-63). smart home orviboWeb14 apr. 2024 · Among 485 patients treated with first-line platinum-based chemotherapy, the probability of initiating maintenance avelumab increased over time following approval . In the 22 months after FDA approval, 99 of 485 patients (20.4%) treated with first-line chemotherapy and 78 of 321 maintenance-eligible patients (24.3%) received … smart home on alexa app

"Web10 nov. 2024 · Thus, associated with the use of platinum agents, expressed regression of the tumor process was observed in 36% of patients, compared with 14.9% of patients against the non-platinum chemotherapy. The results of linear regression analysis confirmed the statistical significance of this finding. " - List of platinum based chemotherapy agents

List of platinum based chemotherapy agents

Web14 apr. 2024 · Among 485 patients treated with first-line platinum-based chemotherapy, the probability of initiating maintenance avelumab increased over time following approval … WebSingle new agents reportedly produce promising response and survival effects, but platinum-based doublets remain the standard chemotherapy for advanced non-small-cell lung cancer (NSCLC). The aim of this study was to evaluate the effectiveness of platinum for advanced NSCLC by carrying out a meta-analysis of trials that compared platinum …

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WebPlatinum compounds (e.g., carboplatin, cisplatin, oxaliplatin) have been central to the practice of oncology for the last 40 years.30 Cisplatin and carboplatin covalently bind to DNA causing intrastrand and interstrand DNA adducts. WebCarboplatin is a chemotherapy drug used for treatment of many types of cancer. The U.S. Food and Drug Administration approved carboplatin for use treating patients with ovarian and non-small cell lung cancer, and oncologists often use carboplatin "off-label" for other cancers. Testicular, stomach, and bladder cancers are among those treated ...

Web1 apr. 2024 · Platinum-based chemotherapy regimens have been proven to be effective in various cancers; however, considerable toxicities may develop and can even lead to treatment discontinuation. Diverse factors may influence adverse treatment events, with pharmacogenetic variations being one prime example. Polymorphisms within the … WebDepending on their characteristics and nature of treatment, chemotherapy agents can be categorized as alkylating agents, antimetabolites, anthracyclines, antitumor antibiotics, monoclonal antibodies, platinums, or plant alkaloids. Here, we discuss the main features of each of these categories. Alkylating agents

Web17 nov. 2024 · Chemotherapy for ovarian cancer is used in neoadjuvant, adjuvant, and maintenance therapy. Agents used include bevacizumab, platinum-based regimens, and poly (ADP-ribose) polymerase (PARP)... WebThis listing includes accelerated approvals (AAs) for malignant hematology and oncology indications that have been subsequently withdrawn, and are therefore, no longer FDA …

WebThe two platinum agents most commonly used for treating metastatic breast cancer are carboplatin and cisplatin. The original version of this review (2004) concluded that …

WebL01XA — Platinum compounds. Drugs. Drug. Drug Description. Cisplatin. A platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors. Nedaplatin. Used in the treatment of non-small cell lung cancer, small cell lung cancer, oesophygeal cancer, and head and neck cancers . Oxaliplatin. hillsborough nj to downingtown pa distanceWeb14 apr. 2024 · Doctors use platinum drugs to treat many kinds of cancer, both alone and in combination with other drugs. Cisplatin, the oldest, has been approved as a cancer treatment since 1978. In the U.S.,... hillsborough nj to cranbury njWeb20 mei 2008 · 19088 Background: Single-agent chemotherapy as a first-line treatment is currently considered as the standard approach for elderly patients with advanced NSCLC. Since the platinum-based combination chemotherapy is the standard treatment for younger patients with advanced NSCLC, it may also have more effective for elderly. We … smart home on raspberry piWeb22 okt. 2024 · Examples of platinum-containing drugs include: cisplatin (Platinol) and a newer type of cisplatin, phenanthriplatin A 2024 study notes that platinum-based … hillsborough nj school scheduleWeb1 mei 2024 · Platinum complex drugs commonly used in chemotherapy as anticancer agents. Pt chemotherapeutics make up roughly 50% of all chemotherapeutic drug regimens. Platinum drugs are used in both Pt (II) and Pt (IV) oxidation states. Pt antitumor complexes have at least three components in common: smart home organizerWeb1 jul. 2001 · Cisplatin (Platinol) isone of the most active drugs in non-small-cell lung cancer (NSCLC), with asingle-agent response rate of approximately 20%. In many different preclinicalmodels, platinum is synergistic with other chemotherapy drugs and withradiation. The superiority of platinum-containing chemotherapy was suggested bya … hillsborough nj township ordinancesWebChemotherapeutic agents, also referred to as antineoplastic agents, are used to directly or indirectly inhibit the uncontrolled growth and proliferation of cancer cells. They are classified according to their mechanism of action and include. alkylating agents. , antimetabolites. , topoisomerase inhibitors. , antibiotics, mitotic inhibitors, and. smart home organization