Hyal2 protein

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August undefined, 2024

Hyaluronidase-2 is a multifunctional protein, previously thought to only possess acid-active hyaluronan-degrading enzymatic function. In humans it is encoded by the HYAL2 gene. This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosami… Web1 sep. 2024 · OBJECTIVE: Hyaluronidases (HYAL1 and HYAL2) are key enzymes in the degradation of hyaluronan, and their expression has been altered in various cancer …

HYAL2 Gene - GeneCards HYAL2 Protein HYAL2 Antibody

WebHyal2 induction was confirmed by using small interfering RNA (siRNA) expressing lentivirus. These in vitro findings correlated in vivo with smokers, where increased Hyal2 immunoreactivity in the epithelium was associated with augmented levels of HA and the appearance of low molecular mass HA species in bronchial secretions. WebPrestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution. Synonym (s): Anti-Hyaluronoglucosaminidase 2, Anti-LUCA2, … msn games bubble town ball

Protein structure - HYAL2 - The Human Protein Atlas

WebRecombinant Human Hyaluronidase 2/HYAL2 His-tag Protein, CF Summary Learn more about Fluorescent Glycan Labeling and Detection Product Specifications Purity >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. Endotoxin Level <1.0 EU per 1 μg of the protein by the LAL method. Activity WebOBJECTIVE: Hyaluronidases (HYAL1 and HYAL2) are key enzymes in the degradation of hyaluronan, and their expression has been altered in various cancer types. We previously showed that hyaluronan accumulation in endometrial carcinomas was correlated with decreased mRNA expression of the HYAL genes. WebRecombinant Human HYAL2 protein is a Wheat germ Protein fragment 340 to 439 aa range and validated in WB, ELISA. Recombinant Human HYAL2 protein (ab152907) … msn games chainz 2 relinked

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Hyal2 protein

Candidate tumor suppressor HYAL2 is a ... - PNAS

WebRecombinant Human HYAL2 Protein, N-His (YHG32601) specific references (0) DATASHEET. Applications：SDS-PAGE, WB, ELISA, Immunogen, Bioactivity testing in progress Expression system：E. coli Accession：Q12891 Protein length：Asn74-Gly432. Overview . Catalog No. YHG32601 Webab68608 staining HYAL2 in JEG3 cells. The cells were fixed with 100% methanol (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions.

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WebTissue proteome. GENERAL INFORMATIONi. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. HYAL2. WebHyaluronidase-2 is a multifunctional protein, previously thought to only possess acid-active hyaluronan -degrading enzymatic function. In humans it is encoded by the HYAL2 gene. [5] [6] [7] This gene encodes a protein which is similar in structure to hyaluronidases.

Web4 jan. 2024 · On the contrary, the protein level of Hyal2 was hardly detectable after mechanical load (Figure 5B). The combined application of the two stresses elevated the expression of Hyal1, Hyal3, and Hyal4. Administration of PACAP neuropeptide together with H 2 O 2 reduced the protein expression of Hyal1, Hyal2, and Hyal4, but further elevation … WebCH DE. Anwendungen Produkte Serviceangebote Support Produkte Serviceangebote Support

WebRecombinant Human HYAL2 Protein, N-His (YHG32601) specific references (0) DATASHEET. Applications：SDS-PAGE, WB, ELISA, Immunogen, Bioactivity testing in … WebHYAL2 PROTEIN STRUCTURE ANTIBODIES AND VALIDATION Protein structures PROTEIN STRUCTUREi Predicted Description: Structure prediction from Alphafold project. Structure version 2 # Chains: 1 # Clinical variants: 0 # Population variants: 296 Antigens: Off On Variants: Off Clinical Population Color scheme: Confidence Residue index Chain …

WebHYAL2 Antibodies Antibodies that detect HYAL2 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target HYAL2 in Human, Mouse and Rat samples. Our HYAL2 polyclonal antibodies are developed in Rabbit and Goat.

WebWhile HYAL1 is a strict lysosomal hyaluronidase and is active when pH ≤ 5.5 (9), HYAL2 is active in a narrow range of pH 5.0 to 5.5 (6) and is attached to cell membrane via GPI … how to make gravy at homeWebHyaluronidase-2 (HYAL2) (AA 21-448) protein (His tag) Crystallography grade HYAL2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, … msn games checkers free downloadWeb12 jan. 2024 · HYAL2, encoding hyaluronidase 2, degrades extracellular hyaluronan, a critical component of the developing heart and palatal shelf matrix. Transfection assays demonstrated that the gene mutations destabilize the molecule, dramatically reducing HYAL2 protein levels. how to make gravy browner