Christopher vakoc
WebThe Vakoc Laboratory Cancer Drug Target Discovery and Mechanisms Our lab seeks to discover drug targets by applying genetic screens to human cancer cells. This genetic … WebChris Vakoc. Cancer Center Member. Professor Harold and Florence & Ethel McNeill Professor of Cancer Research Cancer Center Program Co-Leader. signal transduction, Ras and Rho proteins, tumorigenesis, …
Christopher vakoc
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WebChristopher Vakoc, MD, PhD, is a professor at Cold Spring Harbor Laboratory. His research is focused on gene regulation, specifically determining how certain genes drive cancer growth and looking for ways … WebFeb 24, 2024 · Vakoc, whose lab is next door to CSHL Cancer Center Director David Tuveson, has also starting searching for potential therapeutic targets in pancreatic cancer. He is excited about the potential to bring attention to a possible candidate that may provide a therapeutic benefit for patients at some point.
WebETV6 dependency in Ewing sarcoma by antagonism of EWS-FLI1-mediated enhancer activation. Nat Cell Biol. 2024 Jan 19. doi: 10.1038/s41556-022-01060-1. WebChristopher R. Vakoc, Ph.D. - Publications Affiliations: 2008- Cold Spring Harbor Laboratory, Cold Spring Harbor, NY Area: Molecular Biology Tree Info Grants Similar researchers PubMed Report error 119 high-probability publications. We are testing a new system for linking publications to authors. You can help!
WebMay 12, 2015 · Led by Junwei Shi and Christopher Vakoc, the researchers designed CRISPR/Cas9 systems to knock out 192 specific protein domains in five chromatin regulator genes (rather than knock out the entire gene) to find those essential to the survival of acute myeloid leukemia cells. They found 25 domains without which cancer cells could not … WebChristopher Vakoc Professor Cancer Center Program Co-Leader Alan and Edith Seligson Professor of Cancer Research M.D., Ph.D., University of Pennsylvania, 2007 … CSHL neuroscientists focus on understanding how neural connections … Since the DNA Learning Center was established in 1988, we've been … The Cancer Center at Cold Spring Harbor Laboratory (CSHL) is a basic research … The CSHL Cancer Genomics group seeks to understand how the cancer genome … The plant biology group at CSHL focuses on plant development and gene … Vakoc Laboratory. cancer, genome editing, gene regulation, epigenetics. ... Christina Renna Foundation raises $30K for sarcoma research. 2/2/2024. The … CSHL hosts many events all year long for science enthusiasts of all ages to … The Simons Center for Quantitative Biology (SCQB) is Cold Spring Harbor … From West: Take the Long Island Expressway (Route 495) east to Exit …
WebMar 15, 2024 · Here, we used a domain-focused CRISPR screen to reveal an essential role for LKB1 and its Salt-Inducible Kinase effectors (SIK3, in a partially redundant manner with SIK2) to maintain MEF2C function in acute myeloid leukemia (AML). A key phosphorylation substrate of SIK3 in this context is HDAC4, a repressive cofactor of MEF2C.
WebChristopher R Vakoc A highly aggressive subset of pancreatic ductal adenocarcinomas undergo trans-differentiation into the squamous lineage during disease progression. thicket\u0027s e1WebThe Christopher Vakoc Lab has deposited materials at Addgene for distribution to the research community. Addgene is a nonprofit plasmid repository dedicated to improving … thicket\u0027s dwWebJul 4, 2016 · Dass BRD9 ein Teil der Maschinerie ist, durch die bei der akuten myeloische Leukämie (AML) das Wachstumsgen „Myc“ ständig aktiv ist, konnte das Team um Christopher Vakoc vom Cold Spring Harbor Laboratory in New York (USA) mittels einer groß angelegten Suche belegen. An der Forschungsarbeit waren auch Kollegen vom … thicket\\u0027s dw