Bin2 point mutation

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August undefined, 2024

WebBIN2 functions redundantly with other Arabidopsis GSK3-like kinases to regulate brassinosteroid signaling GLYCOGEN SYNTHASE KINASE3 (GSK3) is a highly conserved serine/threonine kinase involved in a variety … WebGenetic analysis of the bin2 (BR-INSENSITIVE 2) mutant indicated that the BR-insensitive dwarf phenotype was due to a semidominant mutation in the BIN2 gene that mapped …

The GSK3-like Kinase BIN2 Is a Molecular Switch between

WebJul 25, 2024 · Our aim was to find unknown BIN2 regulators via a forward genetic screen for bikinin-resistant mutants in Arabidopsis. Findings: We discovered that a mutation in the ADENOSINE MONOPHOSPHATE DEAMINASE ( AMPD )/ EMBRYONIC FACTOR1 ( FAC1) gene reduces the sensitivity of Arabidopsis seedlings to both bikinin and BRs. WebJan 30, 2024 · For generation the mutant forms of BIN2 and CO, their coding sequences were first cloned into the pQBV3 vector, and then the point mutations were introduced by the specifically designed primers as previously described ( Zheng et al., 2004 ), following the PCR amplification program: preheating at 94°C for 3 min, 16 cycles of 94°C for 1 min, … campingplätze nähe st peter ording

4.8: Mutation Types - Biology LibreTexts

WebJul 11, 2002 · BIN2 encodes a member of the glycogen synthase kinase-3 (GSK3)-like kinases ( 14, 15 ). The increased kinase activity by the semidominant bin2–1 mutation … Webdet2-1 and BR-insensitive mutant bin2-1 are hypersensitive to salinity stress during seed germination and/or the seed-ling growth stage. Moreover, the hypersensitivity corre … WebDec 29, 2024 · To further determine the impact of the mutation on the BR signaling outputs, we expressed native promoter-driven genomic BIN2 and the corresponding mutated variants in Col-0. These mutations led to a larger plant stature (Figs 5d, S8) and the accumulation of more unphosphorylated BES1 compared with the plants expressing wild-type BIN2 (Fig. … fischer 2 via boleto

BIN2 Protein kinase superfamily protein [ (thale cress)]

Frontiers BIN2 phosphorylates the Thr280 of CO to restrict its ...

WebJan 1, 2012 · The kinase-dead mutation bin2 (K69R) that suppresses gain-of-function mutations is highlighted in light green. Homologous residues to those identified by mutation in At SK32 [48] are marked with white arrowheads. The serine 9 residue specific to GSK3β and essential to the regulation of its inhibition is marked with a black arrowhead. WebMar 27, 2024 · HY5 L137D mutation reduces BIN2 activity. To understand which amino acid residues of HY5 were important for its interaction with BIN2, we screened BIN2-interacting sites in the HY5 LZ region. campingplätze languedoc roussillon meerWebBIN2 (brassinosteroid-insensitive 2) kinase, a GSK3-like kinase functioning as a negative regulator in BR signaling, directly phosphorylated RAPTOR1B (regulatory-associated protein of TOR 1B), a... camping platzermuehle neualbenreuth

"WebSep 24, 2024 · TOR is required for BL-mediated hypocotyl growth. Previous studies suggested that the TOR and BR signaling pathways are coordinated, as TOR regulates the BR signaling components BIN2 [Citation 32] and BZR1 [Citation 33].BRs regulate the expression of thousands of genes through transcription factors including BES1 and … " - Bin2 point mutation

Bin2 point mutation

WebGenetic analysis of T-DNA insertional mutations of BIN2 and its two closest homologs. A, Schematic representation of T-DNA insertions in the BIL1 and BIL2 genes. Black boxes represent... WebNov 1, 2002 · BIN2, which is identical to the UCU1 gene implicated in leaf development ( Pérez-Pérez et al., 2002 ), encodes an intracellular Ser/Thr kinase that displays significant sequence identity to the mammalian GSK3 and fruitfly ( Drosophila melanogaster) SHAGGY kinases ( Li and Nam, 2002 ).

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WebNov 1, 2002 · As expected, the bin2-1-mutated BIN2 protein showed a higher kinase activity toward BES1 or BZR1 than the wild-type BIN2, whereas no phosphorylation by the wild … WebJan 1, 2012 · BIN2 encodes a GSK3 with a catalytic domain sharing ∼70% identity with animal GSK3β 17, 18, 19, 20 (Figure 1). Gain-of-function bin2 point mutations and …

WebMar 3, 2024 · A point mutation in BnaC01.BIN2 leads to a dwarf phenotype, and heterozygosity in the BnDF4 allele leads to short stature without marked differences in … WebA gain-of-function mutation in Brassinosteroid-insensitive 2 alters Arabidopsis floral organ development by altering auxin levels Auxin can alter the fertility of bin2-1 plants and depends on the expression of SHY2. Brassinosteroids (BRs) play important roles in plant growth and developmental processes.

WebA reduction in BIN2 gene expression partially suppressed a weak bri1 mutation. (A) Seedlings grown on synthetic medium [from left to right in (A to D)], wild-type, bri1-101, bri1301,... WebBIN2 (brassinosteroid-insensitive 2) kinase, a GSK3-like kinase functioning as a negative regulator in BR signaling, directly phosphorylated RAPTOR1B (regulatory-associated protein of TOR 1B), a ...

WebNov 9, 2024 · The gain-of-function mutant bin2-1 contains an E263K mutation in the catalytic domain of BIN2 and is semidominant, with the homozygous mutant displaying severe growth defects (Li et al., 2001 ). The heterozygous bin2-1 mutant ( bin2-1 HT) was hypersensitive to salt stress ( Figures 2 C and 2E).

WebJan 30, 2024 · For generation the mutant forms of BIN2 and CO, their coding sequences were first cloned into the pQBV3 vector, and then the point mutations were introduced … fischer 3q platiniumWebApr 11, 2024 · Michel De Jaeghere, ancien directeur de la rédaction de l’excellent magazine, "Le Spectacle du monde", et aujourd’hui, responsable des numéros spéciaux du Figaro (le Figaro Histoire, etc.), membre correspondant de l’Académie des sciences morales et politiques, est l’auteur de plusieurs ouvrages dans lesquels il met sa très grande … fischer 344 identificationWebBIN2 functions redundantly with other Arabidopsis GSK3-like kinases to regulate brassinosteroid signaling GLYCOGEN SYNTHASE KINASE3 (GSK3) is a highly … campingplatz eutiner seehttp://sourcedb.ib.cas.cn/cn/ibthesis/201003/P020100329363315667749.pdf fischer 4 bocasWebBIN2_ENST00000604560 - Explore an overview of BIN2_ENST00000604560, with a histogram displaying coding mutations, full tabulated details of all associated variants, tissue distribution and any drug resistance data. campingplatz fehmarn beltWebMar 27, 2024 · HY5 L137D mutation reduces BIN2 activity. To understand which amino acid residues of HY5 were important for its interaction with BIN2, we screened BIN2 … fischer 30 fairway marineWebJan 5, 2024 · Encodes BIN2, a member of the ATSK (shaggy-like kinase) family. BIN2 functions in the cross-talk between auxin and brassinosteroid signaling pathways. BIN2 … fischer 3/4 ton lever chain hoist